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Dr. LIU, Xiaotian

Name: Xiaotian Liu
Status: Research Associate Professor, School of Life Sciences, SUSTech
Contact: Room 412, The Second Research Building, SUSTech
0755-88015415, liuxt@sustech.edu.cn
ORCID: 0000-0001-5009-1287

Education 

  • Ph.D. in Bioengineering, Hong Kong University of Science and Technology 2015-2019 

  • M.Phil. in Biochemistry, Hong Kong University of Science and Technology 2013-2015 

  • B.Sc. in Biotechnology, University of Science and Technology of China 2003-2008 


Professional Experience 

  • Research Assistant Professor, Southern University of Science and Technology 2020-Now 

  • Postdoctoral Fellow, Chinese University of Hong Kong 2019-2020 

  • Research Assistant, Hong Kong University of Science and Technology 2010-2013 

  • Research Assistant, University of Science and Technology of China 2008-2010 


Scholarships, Prizes, Honors and Awards 

  • Hong Kong Technology Talent Scheme Postdoctoral Hub for ITF 2020 

  • Chan Tak Kei & Wong Kwai Ying Bioengineering Student Research Award 2019 

  • HKJEBN Scholarship for Talents 2016-2019 

  • Chinese National Chemistry Contest for High School Students, First Prize 2002 


Publications 

  1. X Hu# , P Yang# , C Chai, J Liu, H Sun, Y Wu, M Zhang, M Zhang*, X Liu*, H Yu*. Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1. Nature (2023).

  2. Fu S# , Shi W# , Luo T, He Y, Zhou L, Yang J, Yang Z, Liu J, Liu X, Guo Z, Yang C, Liu C, Huang Z, Ries J, Zhang M, Xi P, Jin D, Li Y*. Field dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging. Nat Methods (2023).

  3. Fu S# , Shi W# , Luo T, He Y, Zhou L, Yang J, Yang Z, Liu J, Liu X, Guo Z, Yang C, Liu C, Huang Z, Ries J, Zhang M, Xi P, Jin D, Li Y*. Field dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging. bioRxiv (2022).

  4. Wu Y# , Zhang M# , Yang Y# , Ding X, Yang P, Huang K, Hu X, Zhang M, Liu X*, Yu H*. Structures and mechanism of chitin synthase and its inhibition by antifungal drug Nikkomycin Z. Cell Discov 8,129 (2022).

  5. B Jiang# , X Liu#, C Yang# , Z Yang, J Luo, S Kou, K Liu and F Sun*. Injectable, photoresponsive hydrogels for axon regeneration enabled by metal-directed protein assembly. Science Advances, v. 6, (41) (2020).

  6. S Kou, X Yang, Z Yang, X Liu, SV Wegner, F Sun*. Cobalt-Cross-Linked, Redox-Responsive Spy Network Protein Hydrogels. ACS Macro Letters 8, 773-778 (2019).

  7. X Liu, X Yang, Z Yang, J Luo, X Tian, K Liu, S Kou, F Sun*. Versatile engineered protein hydrogelsenabling decoupled mechanical and biochemical tuning for cell adhesion and neurite growth. ACS Applied Nano Materials 1 (4), 1579-1585 (2018).

  8. A Tyagi, X Liu, I Abidi, Z Gao, B Park, X Zeng, X Ou, A Cagang, M Zhuang, M Hossain, K Zhang, L Weng, F Sun, Z Luo. Modular functionalization of crystalline graphene by recombinant proteins: a nanoplatform for probing biomolecules Nanoscale 10 (47), 22572-22582 (2018).

  9. J Luo, X Liu, Z Yang, F Sun*. Synthesis of Entirely Protein-Based Hydrogels by Enzymatic Oxidation Enabling Water-Resistant Bioadhesion and Stem Cell Encapsulation. ACS Applied Bio Materials 1 (5), 1735-1740 (2018).

  10. Wei Z# , Xu Z# , Liu X, Lo WS, Ye F, Lau CF, Wang F, Zhou JJ, Nangle LA, Yang XL, Zhang M*, Schimmel P*. Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase. Nucleic Acids Res. 10.1093 (2016).

  11. Wei Z# , Liu X#, Yu C, Zhang M*. Structural basis of cargo recognitions for class V myosins. Proceedings of the National Academy of Sciences. 9:110 (28):11314-9 (2013).

  12. Wu M# , Tao Y# , Liu X, Zang J*. Structural basis for phosphorylated autoinducer-2 modulation of the oligomerization state of the global transcription regulator LsrR from Escherichia coli. Journal of Biological Chemistry. 288(22):15878-87 (2013).

  13. Liu X, Wu M, Sun D, Zang J*. Cloning, purification, crystallization and preliminary crystallographic analysis of LsrR from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun. 66(Pt 8):913-5 (2010).



    #Co-first author, *Correspondence





Patents 

 1. Fei S, B Jiang, X Liu. 可注射光敏水凝胶及其制备方法和应用. CN 113354835 B (2022).